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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
14.5 DPC

14 matching records from 14 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx2  T-box 2  
Results  Reference
1J:171828 Aanhaanen WT, Boukens BJ, Sizarov A, Wakker V, de Gier-de Vries C, van Ginneken AC, Moorman AF, Coronel R, Christoffels VM, Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice. J Clin Invest. 2011 Feb 1;121(2):534-44
1*J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
1J:213278 Boukens BJ, Sylva M, de Gier-de Vries C, Remme CA, Bezzina CR, Christoffels VM, Coronel R, Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract. Circ Res. 2013 Jul 5;113(2):137-41
1J:337033 Greulich F, Rudat C, Farin HF, Christoffels VM, Kispert A, Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS One. 2016;11(6):e0156787
1*J:332214 Kaiser M, Ludtke TH, Deuper L, Rudat C, Christoffels VM, Kispert A, Trowe MO, TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti. Nat Commun. 2022 Dec 9;13(1):7628
1J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522
1J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189
1J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253
1*J:137603 Pontecorvi M, Goding CR, Richardson WD, Kessaris N, Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis. Gene Expr Patterns. 2008 Jul;8(6):411-7
1J:311888 Prados B, Gomez-Apinaniz P, Papoutsi T, Luxan G, Zaffran S, Perez-Pomares JM, de la Pompa JL, Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death Dis. 2018 Mar 14;9(3):399
1J:304357 Seya D, Ihara D, Shirai M, Kawamura T, Watanabe Y, Nakagawa O, A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis. Dev Growth Differ. 2021 Jan;63(1):82-92
1*J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1J:73310 Sowden JC, Holt JK, Meins M, Smith HK, Bhattacharya SS, Expression of Drosophila omb-Related T-Box Genes in the Developing Human and Mouse Neural Retina. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3095-102
1J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory